| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0588 | Bind_1239 | Bind_0588 | Bind_1239 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_4432 ATP-binding region ATPase domain protein. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.416 |
| Bind_0588 | mscL | Bind_0588 | Bind_3208 | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_4432 ATP-binding region ATPase domain protein. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.426 |
| Bind_1062 | mscL | Bind_1062 | Bind_3208 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.782 |
| Bind_1062 | polA | Bind_1062 | Bind_2744 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.434 |
| Bind_1062 | recA | Bind_1062 | Bind_2403 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.492 |
| Bind_1062 | ribH | Bind_1062 | Bind_0206 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.870 |
| Bind_1239 | Bind_0588 | Bind_1239 | Bind_0588 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_4432 ATP-binding region ATPase domain protein. | 0.416 |
| Bind_1239 | Bind_1858 | Bind_1239 | Bind_1858 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.688 |
| Bind_1239 | mscL | Bind_1239 | Bind_3208 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.437 |
| Bind_1858 | Bind_1239 | Bind_1858 | Bind_1239 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.688 |
| Bind_1858 | mscL | Bind_1858 | Bind_3208 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.404 |
| Bind_3209 | mscL | Bind_3209 | Bind_3208 | Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: xau:Xaut_0300 aminotransferase class I and II. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.516 |
| mscL | Bind_0588 | Bind_3208 | Bind_0588 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mex:Mext_4432 ATP-binding region ATPase domain protein. | 0.426 |
| mscL | Bind_1062 | Bind_3208 | Bind_1062 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.782 |
| mscL | Bind_1239 | Bind_3208 | Bind_1239 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.437 |
| mscL | Bind_1858 | Bind_3208 | Bind_1858 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.404 |
| mscL | Bind_3209 | Bind_3208 | Bind_3209 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: xau:Xaut_0300 aminotransferase class I and II. | 0.516 |
| mscL | polA | Bind_3208 | Bind_2744 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.492 |
| mscL | recA | Bind_3208 | Bind_2403 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.403 |
| mscL | ribH | Bind_3208 | Bind_0206 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.813 |