| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_2192 | Bind_3415 | Bind_2192 | Bind_3415 | TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: rpa:RPA2669 hypothetical protein. | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | 0.402 |
| Bind_2307 | Bind_3415 | Bind_2307 | Bind_3415 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | 0.413 |
| Bind_2307 | topA | Bind_2307 | Bind_3417 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.586 |
| Bind_3396 | Bind_3415 | Bind_3396 | Bind_3415 | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: azo:azo1220 conserved hypothetical aromatic/alkene monooxygenase, subunit gamma. | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | 0.553 |
| Bind_3414 | Bind_3415 | Bind_3414 | Bind_3415 | KEGG: gbe:GbCGDNIH1_1127 hypothetical protein. | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | 0.625 |
| Bind_3414 | rnr | Bind_3414 | Bind_3416 | KEGG: gbe:GbCGDNIH1_1127 hypothetical protein. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.500 |
| Bind_3414 | topA | Bind_3414 | Bind_3417 | KEGG: gbe:GbCGDNIH1_1127 hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.408 |
| Bind_3415 | Bind_2192 | Bind_3415 | Bind_2192 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: rpa:RPA2669 hypothetical protein. | 0.402 |
| Bind_3415 | Bind_2307 | Bind_3415 | Bind_2307 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.413 |
| Bind_3415 | Bind_3396 | Bind_3415 | Bind_3396 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: azo:azo1220 conserved hypothetical aromatic/alkene monooxygenase, subunit gamma. | 0.553 |
| Bind_3415 | Bind_3414 | Bind_3415 | Bind_3414 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | KEGG: gbe:GbCGDNIH1_1127 hypothetical protein. | 0.625 |
| Bind_3415 | rnr | Bind_3415 | Bind_3416 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.620 |
| Bind_3415 | topA | Bind_3415 | Bind_3417 | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.511 |
| rnr | Bind_3414 | Bind_3416 | Bind_3414 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | KEGG: gbe:GbCGDNIH1_1127 hypothetical protein. | 0.500 |
| rnr | Bind_3415 | Bind_3416 | Bind_3415 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | 0.620 |
| rnr | topA | Bind_3416 | Bind_3417 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.740 |
| topA | Bind_2307 | Bind_3417 | Bind_2307 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.586 |
| topA | Bind_3414 | Bind_3417 | Bind_3414 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | KEGG: gbe:GbCGDNIH1_1127 hypothetical protein. | 0.408 |
| topA | Bind_3415 | Bind_3417 | Bind_3415 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: mex:Mext_2677 mandelate racemase/muconate lactonizing protein. | 0.511 |
| topA | rnr | Bind_3417 | Bind_3416 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.740 |