| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0125 | Bind_2163 | Bind_0125 | Bind_2163 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.999 |
| Bind_0125 | Bind_2165 | Bind_0125 | Bind_2165 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | 0.910 |
| Bind_0125 | Bind_3522 | Bind_0125 | Bind_3522 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | PFAM: thiamine monophosphate synthase; KEGG: rpe:RPE_4721 thiamine monophosphate synthase. | 0.977 |
| Bind_0125 | thiC | Bind_0125 | Bind_0063 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.991 |
| Bind_0125 | thiG | Bind_0125 | Bind_2164 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.936 |
| Bind_0125 | thiL | Bind_0125 | Bind_0208 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.439 |
| Bind_0667 | Bind_3426 | Bind_0667 | Bind_3426 | PFAM: conserved hypothetical protein; KEGG: mex:Mext_1983 hypothetical protein; Belongs to the UPF0262 family. | KEGG: mex:Mext_3229 cobalt chelatase, pCobT subunit; TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase CobT subunit; SMART: von Willebrand factor type A. | 0.627 |
| Bind_0667 | Bind_3522 | Bind_0667 | Bind_3522 | PFAM: conserved hypothetical protein; KEGG: mex:Mext_1983 hypothetical protein; Belongs to the UPF0262 family. | PFAM: thiamine monophosphate synthase; KEGG: rpe:RPE_4721 thiamine monophosphate synthase. | 0.629 |
| Bind_0667 | atpF1 | Bind_0667 | Bind_0740 | PFAM: conserved hypothetical protein; KEGG: mex:Mext_1983 hypothetical protein; Belongs to the UPF0262 family. | H+transporting two-sector ATPase B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.577 |
| Bind_2163 | Bind_0125 | Bind_2163 | Bind_0125 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.999 |
| Bind_2163 | Bind_2165 | Bind_2163 | Bind_2165 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | 0.987 |
| Bind_2163 | Bind_3522 | Bind_2163 | Bind_3522 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | PFAM: thiamine monophosphate synthase; KEGG: rpe:RPE_4721 thiamine monophosphate synthase. | 0.900 |
| Bind_2163 | thiC | Bind_2163 | Bind_0063 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.853 |
| Bind_2163 | thiG | Bind_2163 | Bind_2164 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.997 |
| Bind_2163 | thiL | Bind_2163 | Bind_0208 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.919 |
| Bind_2165 | Bind_0125 | Bind_2165 | Bind_0125 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.910 |
| Bind_2165 | Bind_2163 | Bind_2165 | Bind_2163 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.987 |
| Bind_2165 | Bind_3522 | Bind_2165 | Bind_3522 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | PFAM: thiamine monophosphate synthase; KEGG: rpe:RPE_4721 thiamine monophosphate synthase. | 0.791 |
| Bind_2165 | thiC | Bind_2165 | Bind_0063 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.928 |
| Bind_2165 | thiG | Bind_2165 | Bind_2164 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |