| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0767 | Bind_1507 | Bind_0767 | Bind_1507 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.916 |
| Bind_0767 | Bind_2199 | Bind_0767 | Bind_2199 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.955 |
| Bind_0767 | Bind_2747 | Bind_0767 | Bind_2747 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: atc:AGR_C_4790 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.921 |
| Bind_0767 | Bind_2749 | Bind_0767 | Bind_2749 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | KEGG: mex:Mext_3602 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.907 |
| Bind_0767 | Bind_2750 | Bind_0767 | Bind_2750 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: bme:BMEI0160 succinate dehydrogenase hydrophobic membrane anchor protein. | 0.900 |
| Bind_0767 | Bind_2751 | Bind_0767 | Bind_2751 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: nwi:Nwi_2798 succinate dehydrogenase, cytochrome b subunit. | 0.905 |
| Bind_0767 | Bind_3608 | Bind_0767 | Bind_3608 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.916 |
| Bind_0767 | sucC | Bind_0767 | Bind_3605 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.970 |
| Bind_0767 | sucD | Bind_0767 | Bind_3606 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.942 |
| Bind_1507 | Bind_0767 | Bind_1507 | Bind_0767 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | 0.916 |
| Bind_1507 | Bind_2199 | Bind_1507 | Bind_2199 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.817 |
| Bind_1507 | Bind_2747 | Bind_1507 | Bind_2747 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: atc:AGR_C_4790 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.633 |
| Bind_1507 | Bind_2749 | Bind_1507 | Bind_2749 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: mex:Mext_3602 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.461 |
| Bind_1507 | Bind_2751 | Bind_1507 | Bind_2751 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: nwi:Nwi_2798 succinate dehydrogenase, cytochrome b subunit. | 0.453 |
| Bind_1507 | Bind_3607 | Bind_1507 | Bind_3607 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: xau:Xaut_0156 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. | 0.987 |
| Bind_1507 | Bind_3608 | Bind_1507 | Bind_3608 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.474 |
| Bind_1507 | sucC | Bind_1507 | Bind_3605 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.966 |
| Bind_1507 | sucD | Bind_1507 | Bind_3606 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.945 |
| Bind_2199 | Bind_0767 | Bind_2199 | Bind_0767 | KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | 0.955 |
| Bind_2199 | Bind_1507 | Bind_2199 | Bind_1507 | KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.817 |