Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0010PFAM: ABC-2 type transporter; KEGG: bbt:BBta_5948 ABC transporter permease. (280 aa)    
Predicted Functional Partners:
Msil_0009
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bid:Bind_0009 ABC transporter related.
 
  
 0.971
Msil_0008
TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; KEGG: mrd:Mrad2831_2720 40-residue YVTN family beta-propeller repeat protein.
 
   
 0.918
Msil_0007
KEGG: bbt:BBta_5945 hypothetical protein.
 
     0.913
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
      0.898
Msil_3146
KEGG: rpe:RPE_4682 hypothetical protein.
 
     0.793
Msil_0012
KEGG: bja:blr6199 ABC transporter substrate-binding protein.
 
     0.792
Msil_3145
TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; KEGG: gbe:GbCGDNIH1_1915 surface antigen.
 
   
 0.790
Msil_0196
TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein; KEGG: xau:Xaut_0031 YVTN beta-propeller repeat-containing protein.
 
   
 0.758
Msil_2260
TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: Pyrrolo-quinoline quinone; KEGG: bja:blr6213 methanol dehydrogenase large subunit-like protein.
  
     0.738
Msil_1587
TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: Pyrrolo-quinoline quinone; KEGG: bja:blr6213 methanol dehydrogenase large subunit-like protein.
  
     0.737
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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