Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0100TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bid:Bind_1245 NAD(P)H quinone oxidoreductase, PIG3 family. (328 aa)    
Predicted Functional Partners:
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
  
 
 0.840
Msil_1223
PFAM: Beta-ketoacyl synthase; KEGG: bid:Bind_3487 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
  
 0.820
Msil_0099
PFAM: protein of unknown function DUF81; KEGG: bbt:BBta_4771 hypothetical protein.
       0.689
Msil_0101
SMART: regulatory protein ArsR; KEGG: rpa:RPA2256 ArsR family transcriptional regulator ArsR1.
       0.625
Msil_1247
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_0846 amino acid adenylation domain protein.
  
 
 0.574
Msil_0893
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.569
Msil_0102
TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: nwi:Nwi_3125 arsenate reductase.
       0.539
Msil_0104
TIGRFAM: arsenical resistance protein ArsH; PFAM: NADPH-dependent FMN reductase; KEGG: nha:Nham_4428 NADPH-dependent FMN reductase.
     
 0.483
Msil_0103
TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: rpc:RPC_0616 bile acid:sodium symporter.
       0.452
Msil_2987
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: pzu:PHZ_p0134 pyruvate:ferredoxin oxidoreductase.
     
 0.421
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
Server load: low (16%) [HD]