Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_0122Glutathione-disulfide reductase; Maintains high levels of reduced glutathione. (474 aa)    
Predicted Functional Partners:
Msil_0520
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.993
gshB
KEGG: bid:Bind_3126 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
  
  
 0.947
Msil_2453
PFAM: glutathione peroxidase; KEGG: pzu:PHZ_c1981 glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.944
Msil_1865
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: bid:Bind_2792 thioredoxin.
  
 
 0.942
Msil_1740
PFAM: Glutathione S-transferase domain; KEGG: mca:MCA1303 glutathione S-transferase.
  
 0.940
Msil_3681
PFAM: Glutathione S-transferase domain; KEGG: bid:Bind_3313 glutathione S-transferase domain.
   
 0.939
Msil_1590
PFAM: Glutathione S-transferase domain; KEGG: azc:AZC_3140 putative glutathione S-transferase family protein.
   
 0.938
Msil_0753
PFAM: Glutathione S-transferase domain; KEGG: bid:Bind_1672 glutathione S-transferase domain.
  
 0.930
Msil_0624
PFAM: Glutathione S-transferase domain; KEGG: bid:Bind_1959 glutathione S-transferase domain.
  
 0.929
Msil_1257
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
 
  
 0.927
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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