node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msil_0159 | Msil_1268 | Msil_0159 | Msil_1268 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: mca:MCA1205 sigma-54 dependent transcriptional regulator. | 0.794 |
Msil_0159 | Msil_1646 | Msil_0159 | Msil_1646 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: bid:Bind_3392 GAF modulated sigma54 specific transcriptional regulator, fis family. | 0.790 |
Msil_0159 | Msil_3648 | Msil_0159 | Msil_3648 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Transcriptional regulator, NifA, Fis Family; KEGG: bbt:BBta_5933 NifA subfamily transcriptional regulator; TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase. | 0.844 |
Msil_0159 | Msil_3766 | Msil_0159 | Msil_3766 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: bbt:BBta_0458 two-component response regulator protein. | 0.791 |
Msil_0159 | dnaA | Msil_0159 | Msil_0001 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.817 |
Msil_0159 | ntrC | Msil_0159 | Msil_0529 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Nitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.792 |
Msil_0159 | rpoA | Msil_0159 | Msil_2991 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.941 |
Msil_0159 | rpoB | Msil_0159 | Msil_3868 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.910 |
Msil_0159 | rpoC | Msil_0159 | Msil_3869 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.922 |
Msil_0159 | rpoZ | Msil_0159 | Msil_0999 | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.911 |
Msil_1268 | Msil_0159 | Msil_1268 | Msil_0159 | GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: mca:MCA1205 sigma-54 dependent transcriptional regulator. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.794 |
Msil_1646 | Msil_0159 | Msil_1646 | Msil_0159 | GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: bid:Bind_3392 GAF modulated sigma54 specific transcriptional regulator, fis family. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.790 |
Msil_3648 | Msil_0159 | Msil_3648 | Msil_0159 | Transcriptional regulator, NifA, Fis Family; KEGG: bbt:BBta_5933 NifA subfamily transcriptional regulator; TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.844 |
Msil_3766 | Msil_0159 | Msil_3766 | Msil_0159 | Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: bbt:BBta_0458 two-component response regulator protein. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.791 |
dnaA | Msil_0159 | Msil_0001 | Msil_0159 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.817 |
dnaA | rpoB | Msil_0001 | Msil_3868 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.548 |
dnaA | rpoC | Msil_0001 | Msil_3869 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.401 |
ntrC | Msil_0159 | Msil_0529 | Msil_0159 | Nitrogen metabolism transcriptional regulator, NtrC, Fis Family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.792 |
rpoA | Msil_0159 | Msil_2991 | Msil_0159 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.941 |
rpoA | rpoB | Msil_2991 | Msil_3868 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |