Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_0160TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: bid:Bind_2914 PTS IIA-like nitrogen-regulatory protein PtsN. (153 aa)    
Predicted Functional Partners:
Msil_2821
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: mrd:Mrad2831_0203 putative PTS IIA-like nitrogen-regulatory protein PtsN.
  
  
 
0.914
Msil_1563
PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: bid:Bind_0890 PTSINtr with GAF domain, PtsP; Belongs to the PEP-utilizing enzyme family.
  
   
 0.789
Msil_0251
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: bid:Bind_2737 phosphotransferase system, phosphocarrier protein HPr.
 
  
 0.745
Msil_0252
PFAM: PTS system fructose subfamily IIA component; KEGG: bid:Bind_2738 PTS system fructose subfamily IIA component.
 
  
 0.741
Msil_0159
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.606
Msil_1677
KEGG: bid:Bind_1221 cold-shock protein DNA-binding.
  
  
 0.496
Msil_2987
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: pzu:PHZ_p0134 pyruvate:ferredoxin oxidoreductase.
     
 0.451
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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