Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0187KEGG: bid:Bind_1951 hypothetical protein. (240 aa)    
Predicted Functional Partners:
Msil_0186
PFAM: NADH:ubiquinone oxidoreductase 17.2 kD subunit; KEGG: bid:Bind_1952 NADH:ubiquinone oxidoreductase 17.2 kD subunit.
 
   
 0.851
Msil_0656
PFAM: SmpA/OmlA domain protein; KEGG: bid:Bind_3383 SmpA/OmlA domain protein.
  
     0.654
Msil_1361
SMART: nuclease (SNase domain protein); KEGG: bid:Bind_3161 nuclease (SNase domain protein).
  
     0.612
Msil_0319
PFAM: heat shock protein DnaJ domain protein; KEGG: bid:Bind_3428 heat shock protein DnaJ domain protein.
  
     0.597
Msil_1673
PFAM: ROSMUCR transcriptional regulator; KEGG: bid:Bind_1642 transcriptional regulator, MucR family.
  
     0.592
Msil_1010
PFAM: protein of unknown function DUF1465; KEGG: bid:Bind_3249 protein of unknown function DUF1465.
  
     0.587
Msil_0339
TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: bid:Bind_0222 DNA polymerase III, delta subunit.
  
     0.575
Msil_0448
KEGG: bid:Bind_1816 hypothetical protein.
  
     0.575
Msil_0006
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
     0.567
Msil_1137
PFAM: Protein of unknown function DUF1790; KEGG: bid:Bind_1259 protein of unknown function DUF1790.
  
     0.565
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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