Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Msil_0193PFAM: O-methyltransferase family 3; KEGG: bid:Bind_1677 O-methyltransferase family 3. (222 aa)    
Predicted Functional Partners:
Msil_0194
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: bid:Bind_0850 aminopeptidase N.
     
 0.753
Msil_0548
PFAM: ETC complex I subunit conserved region; KEGG: bid:Bind_1550 ETC complex I subunit conserved region.
  
  
 0.599
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
      0.511
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
  
 
 0.510
Msil_0195
KEGG: bja:bll4707 hypothetical protein.
     
 0.503
Msil_0196
TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein; KEGG: xau:Xaut_0031 YVTN beta-propeller repeat-containing protein.
       0.426
Msil_0192
KEGG: bid:Bind_2033 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
  
 0.411
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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