Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0366PFAM: protein of unknown function DUF1491; KEGG: bid:Bind_1656 protein of unknown function DUF1491. (112 aa)    
Predicted Functional Partners:
Msil_0365
PFAM: protein of unknown function DUF1311; KEGG: rru:Rru_A0482 hypothetical protein.
       0.737
Msil_1425
PFAM: protein of unknown function DUF1674; KEGG: bid:Bind_2072 protein of unknown function DUF1674.
  
     0.673
Msil_1558
PFAM: HemY domain protein; KEGG: bid:Bind_1190 HemY domain protein.
  
     0.633
Msil_1017
PFAM: 2-deoxycytidine 5-triphosphate deaminase; KEGG: bid:Bind_1037 2-deoxycytidine 5-triphosphate deaminase.
  
     0.631
Msil_1000
PFAM: protein of unknown function DUF88; KEGG: bid:Bind_2447 protein of unknown function DUF88.
 
     0.627
Msil_2270
PFAM: protein of unknown function DUF1355; KEGG: bid:Bind_3475 hypothetical protein.
  
     0.621
Msil_3815
KEGG: bid:Bind_0051 hypothetical protein.
  
     0.619
Msil_2330
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: bid:Bind_3530 integral membrane sensor signal transduction histidine kinase.
 
     0.617
hisS
histidyl-tRNA synthetase; KEGG: bid:Bind_1776 histidine--tRNA ligase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein.
  
     0.576
Msil_0803
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
  
     0.550
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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