Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_0404Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: azc:AZC_1079 transcriptional regulator. (299 aa)    
Predicted Functional Partners:
Msil_0405
Glucan 1,4-alpha-glucosidase; PFAM: glycoside hydrolase 15-related; KEGG: rru:Rru_A3302 glucan 1,4-alpha-glucosidase.
       0.773
Msil_0406
KEGG: rru:Rru_A3301 hypothetical protein.
       0.773
Msil_3658
KEGG: bja:bsl3134 putative NAD-dependent formate dehydrogenase.
  
   
 0.711
Msil_0407
PFAM: SbmABacA family protein; ABC transporter domain protein; KEGG: rru:Rru_A3300 ABC transporter component.
       0.651
Msil_3656
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: xau:Xaut_3479 formate dehydrogenase, alpha subunit.
 
     0.556
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
  
     0.523
Msil_0403
KEGG: bid:Bind_1241 hypothetical protein.
       0.516
Msil_3794
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: xau:Xaut_4335 LysR family transcriptional regulator.
  
     0.508
Msil_0408
PFAM: glycoside hydrolase family 3 domain protein; KEGG: rru:Rru_A3299 glycoside hydrolase family protein.
     
 0.412
Msil_3233
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bid:Bind_2471 transcriptional regulator, LysR family.
  
     0.406
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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