Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0432PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: mrd:Mrad2831_4968 peptidase S1 and S6 chymotrypsin/Hap. (248 aa)    
Predicted Functional Partners:
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.819
Msil_1972
KEGG: nha:Nham_0594 hypothetical protein.
    
 0.780
Msil_3148
PFAM: Ankyrin; SMART: extracellular solute-binding protein family 3; KEGG: xcv:XCV0710 hypothetical protein.
    
 0.780
Msil_1074
PFAM: peptidase C15 pyroglutamyl peptidase I; KEGG: bid:Bind_1658 peptidase C15 pyroglutamyl peptidase I.
    
 
 0.769
Msil_0500
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: mex:Mext_0324 MIP family channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.767
Msil_2212
PFAM: protein of unknown function DUF339; KEGG: bid:Bind_0893 protein of unknown function DUF339.
   
   0.749
Msil_0674
KEGG: bid:Bind_2935 HSP70 family molecular chaperone.
    
 0.737
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.737
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
    
   0.736
Msil_0844
PFAM: histone deacetylase superfamily; KEGG: bid:Bind_0946 histone deacetylase superfamily.
    
  0.724
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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