Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_0433KEGG: bid:Bind_2227 hypothetical protein. (107 aa)    
Predicted Functional Partners:
Msil_0435
PFAM: ATP-binding region ATPase domain protein; KEGG: bid:Bind_2229 integral membrane sensor signal transduction histidine kinase.
  
  
 0.693
Msil_0432
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: mrd:Mrad2831_4968 peptidase S1 and S6 chymotrypsin/Hap.
       0.564
Msil_0436
TIGRFAM: cytochrome c-type biogenesis protein CcmI; KEGG: bid:Bind_2230 cytochrome c-type biogenesis protein CcmI.
       0.558
Msil_0434
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rpt:Rpal_2126 two component transcriptional regulator, winged helix family.
  
  
 0.550
ccmE
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
       0.535
Msil_0438
PFAM: cytochrome c assembly protein; KEGG: bid:Bind_2232 cytochrome c-type biogenesis protein CcmF.
       0.518
Msil_0439
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
       0.518
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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