Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0488Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (774 aa)    
Predicted Functional Partners:
Msil_1672
PFAM: Fe-S metabolism associated SufE; KEGG: bid:Bind_1641 Fe-S metabolism associated SufE.
 
 0.979
Msil_1607
KEGG: bid:Bind_0099 FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.968
Msil_1608
TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: bid:Bind_0098 FeS assembly protein SufB.
 
 
 0.943
Msil_1606
TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: bid:Bind_0100 FeS assembly protein SufD.
 
 
 0.940
Msil_3621
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 
 0.917
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
    
 0.911
Msil_2331
PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: aba:Acid345_1748 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
  0.910
Msil_0328
KEGG: nha:Nham_0684 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
     
 0.906
Msil_2812
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bid:Bind_0056 thioredoxin reductase.
  
 
  0.906
Msil_3550
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: bid:Bind_2345 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
  0.906
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.