Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0841KEGG: bid:Bind_3194 integral membrane protein-like protein. (339 aa)    
Predicted Functional Partners:
Msil_0840
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bid:Bind_3196 histidine kinase.
     
 0.534
Msil_2862
KEGG: bid:Bind_1008 hypothetical protein.
  
     0.531
Msil_1669
PFAM: Peptidoglycan-binding domain 1 protein; KEGG: bid:Bind_1638 peptidoglycan-binding domain 1 protein.
  
     0.528
Msil_0900
KEGG: bid:Bind_2305 hypothetical protein.
  
     0.453
Msil_1594
KEGG: bid:Bind_0659 putative exported protein of unknown function.
  
     0.437
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
  
     0.429
Msil_0121
KEGG: bid:Bind_0880 hypothetical protein.
  
     0.428
Msil_0950
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: bid:Bind_0116 transcriptional regulator, XRE family.
  
     0.425
Msil_1618
KEGG: bid:Bind_0013 hypothetical protein.
  
     0.400
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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