Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_0983KEGG: bid:Bind_0924 hypothetical protein. (84 aa)    
Predicted Functional Partners:
Msil_2751
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: hch:HCH_00108 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.
    
   0.878
Msil_0982
PFAM: monooxygenase FAD-binding; KEGG: bid:Bind_0923 monooxygenase FAD-binding.
 
     0.802
nuoD
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
   
   0.790
Msil_0448
KEGG: bid:Bind_1816 hypothetical protein.
  
     0.774
Msil_1090
PFAM: conserved hypothetical protein; KEGG: bid:Bind_0715 hypothetical protein.
  
     0.774
Msil_2528
KEGG: bid:Bind_0268 hypothetical protein.
  
     0.774
Msil_1236
PFAM: Invasion associated locus B family protein; KEGG: bid:Bind_0731 invasion associated locus B family protein.
  
     0.773
Msil_2304
KEGG: rpb:RPB_3925 hypothetical protein.
  
     0.772
Msil_3701
PFAM: protein of unknown function DUF1036; KEGG: bid:Bind_3233 protein of unknown function DUF1036.
  
     0.772
Msil_3808
KEGG: bid:Bind_1070 hypothetical protein.
  
     0.769
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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