Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_1000PFAM: protein of unknown function DUF88; KEGG: bid:Bind_2447 protein of unknown function DUF88. (205 aa)    
Predicted Functional Partners:
Msil_1001
PFAM: Uracil-DNA glycosylase superfamily; KEGG: bid:Bind_2448 uracil-DNA glycosylase superfamily.
       0.739
Msil_0366
PFAM: protein of unknown function DUF1491; KEGG: bid:Bind_1656 protein of unknown function DUF1491.
 
     0.627
Msil_1899
KEGG: bid:Bind_0431 methyltransferase type 11.
  
     0.553
Msil_2368
KEGG: bja:bll3586 hypothetical protein.
  
  
 0.541
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.541
Msil_2220
PFAM: DNA polymerase III chi subunit HolC; KEGG: bid:Bind_0649 DNA polymerase III chi subunit HolC.
  
     0.507
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.503
Msil_2113
PFAM: regulatory protein MarR; KEGG: bid:Bind_0883 transcriptional regulator, MarR family.
  
     0.491
pheT
KEGG: bid:Bind_3247 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.422
Msil_0998
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
       0.402
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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