Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_1002Non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; non-ribosomal peptide synthetase; PFAM: AMP-dependent synthetase and ligase; transferase hexapeptide repeat containing protein; KEGG: bid:Bind_1102 non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family. (1358 aa)    
Predicted Functional Partners:
Msil_1246
PFAM: Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: bid:Bind_0847 condensation domain protein.
  
 0.955
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
 
 
 0.955
Msil_1248
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; KEGG: npu:Npun_R6591 amino acid adenylation domain-containing protein.
 
 
0.869
cysS
KEGG: bid:Bind_1915 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.789
Msil_1247
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_0846 amino acid adenylation domain protein.
 
  
0.777
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.761
Msil_1224
KEGG: bid:Bind_3488 hypothetical protein.
  
 
 0.761
Msil_2088
KEGG: bid:Bind_2076 membrane protein involved in the export of O-antigen and teichoic acid-like protein.
 
  
 0.737
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
 
 0.734
Msil_3806
PFAM: 4'-phosphopantetheinyl transferase; KEGG: mar:MAE_07060 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
 
 
 0.711
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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