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purA protein (Methylocella silvestris) - STRING interaction network
"purA" - Adenylosuccinate synthetase in Methylocella silvestris
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (431 aa)    
Predicted Functional Partners:
Msil_1095
TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; KEGG- bid-Bind_2682 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (435 aa)
 
 
  0.988
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (496 aa)
 
 
  0.988
purH
Bifunctional purine biosynthesis protein PurH; KEGG- bid-Bind_1287 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- MGS domain protein; AICARFT/IMPCHase bienzyme formylation region (530 aa)
 
  0.985
pyrB
TIGRFAM- aspartate carbamoyltransferase; PFAM- aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG- bid-Bind_3418 aspartate carbamoyltransferase; Belongs to the ATCase/OTCase family (316 aa)
 
 
  0.962
argG
PFAM- argininosuccinate synthase; KEGG- bid-Bind_1273 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily (416 aa)
   
 
  0.947
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (534 aa)
 
   
  0.937
Msil_2981
PFAM- Asparaginase/glutaminase; KEGG- mpo-Mpop_0827 asparaginase/glutaminase (327 aa)
 
  0.920
Msil_0296
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate (506 aa)
         
  0.912
Msil_2961
PFAM- aminotransferase class I and II; KEGG- bid-Bind_0079 aminotransferase class I and II (400 aa)
   
 
  0.910
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (252 aa)
   
 
    0.909
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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