Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msil_1074PFAM: peptidase C15 pyroglutamyl peptidase I; KEGG: bid:Bind_1658 peptidase C15 pyroglutamyl peptidase I. (286 aa)    
Predicted Functional Partners:
Msil_0500
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: mex:Mext_0324 MIP family channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.809
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.796
Msil_0432
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: mrd:Mrad2831_4968 peptidase S1 and S6 chymotrypsin/Hap.
    
 
 0.769
Msil_0844
PFAM: histone deacetylase superfamily; KEGG: bid:Bind_0946 histone deacetylase superfamily.
    
   0.738
Msil_1308
PFAM: histone deacetylase superfamily; KEGG: mlo:mlr7469 histone deacetylase.
    
   0.738
Msil_1197
KEGG: rpt:Rpal_1749 CbbX protein; TIGRFAM: CbbX protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
    
   0.734
Msil_1771
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: azc:AZC_3408 ATPase.
    
   0.734
Msil_1758
KEGG: nha:Nham_0836 hypothetical protein.
   
   0.731
Msil_3020
SMART: WD-40 repeat protein; KEGG: bid:Bind_3116 WD-40 repeat protein.
   
   0.731
Msil_2879
PFAM: Stage II sporulation E family protein; Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: met:M446_0912 protein serine/threonine phosphatase.
    
   0.729
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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