Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_1233TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: bid:Bind_3645 lytic murein transglycosylase. (405 aa)    
Predicted Functional Partners:
Msil_1234
PFAM: response regulator receiver; KEGG: mpo:Mpop_3474 response regulator receiver protein.
       0.494
Msil_3479
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: bid:Bind_0686 peptidoglycan glycosyltransferase.
   
 
 0.483
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
     
 0.422
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
     0.414
Msil_0728
N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: bid:Bind_0933 N-acetylmuramoyl-L-alanine amidase.
     
 0.410
Msil_3546
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mrd:Mrad2831_2007 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD.
     
 0.406
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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