Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msil_1335PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bid:Bind_1929 integral membrane sensor signal transduction histidine kinase. (518 aa)    
Predicted Functional Partners:
Msil_0423
PFAM: response regulator receiver; KEGG: bid:Bind_1212 response regulator receiver protein.
 
 
 0.991
Msil_0424
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: rpe:RPE_3385 response regulator PleD.
 0.987
Msil_0192
KEGG: bid:Bind_2033 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 
0.929
Msil_1887
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: lch:Lcho_0045 adenylate/guanylate cyclase.
 
 0.850
Msil_0520
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.799
Msil_0834
Two component transcriptional regulator PhoB, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bid:Bind_3413 two component transcriptional regulator, winged helix family.
 
 
 0.765
Msil_1234
PFAM: response regulator receiver; KEGG: mpo:Mpop_3474 response regulator receiver protein.
 
 
 0.731
Msil_2511
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bid:Bind_3546 two component transcriptional regulator, winged helix family.
 
 
 0.730
Msil_2529
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bid:Bind_0344 two component transcriptional regulator, winged helix family.
 
 
 0.692
Msil_2822
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mlo:mll3126 two-component response regulator.
 
 
 0.668
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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