Msil_1372 protein (Methylocella silvestris) - STRING interaction network

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Msil_1372

KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (132 aa)

Predicted Functional Partners:

Msil_1373

0.725

dnaK

0.649

Msil_0747

0.590

clpB

0.590

Msil_2366

0.590

Msil_1256

0.573

Msil_3672

0.568

Msil_3723

0.540

htpG

0.491

grpE

0.491

Your Current Organism:

Methylocella silvestris

NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Msil_0747	Msil_1372	Msil_0747	Msil_1372	KEGG: bid:Bind_1667 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	0.590
Msil_0747	dnaK	Msil_0747	Msil_2955	KEGG: bid:Bind_1667 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.893
Msil_0747	grpE	Msil_0747	Msil_2800	KEGG: bid:Bind_1667 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.716
Msil_0747	htpG	Msil_0747	Msil_1910	KEGG: bid:Bind_1667 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.705
Msil_1256	Msil_1372	Msil_1256	Msil_1372	KEGG: bid:Bind_0717 hypothetical protein.	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	0.573
Msil_1372	Msil_0747	Msil_1372	Msil_0747	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	KEGG: bid:Bind_1667 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; ATP-dependent Clp protease ATP-binding subunit clpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	0.590
Msil_1372	Msil_1256	Msil_1372	Msil_1256	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	KEGG: bid:Bind_0717 hypothetical protein.	0.573
Msil_1372	Msil_1373	Msil_1372	Msil_1373	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	PFAM: protein of unknown function DUF1150; KEGG: bid:Bind_0513 protein of unknown function DUF1150.	0.725
Msil_1372	Msil_2366	Msil_1372	Msil_2366	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	Type VI secretion ATPase, ClpV1 family; KEGG: bja:bll3587 ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	0.590
Msil_1372	Msil_3672	Msil_1372	Msil_3672	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	KEGG: art:Arth_3633 hypothetical protein.	0.568
Msil_1372	Msil_3723	Msil_1372	Msil_3723	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	PFAM: Erythromycin esterase; KEGG: cak:Caul_4233 erythromycin esterase.	0.540
Msil_1372	clpB	Msil_1372	Msil_1907	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.	0.590
Msil_1372	dnaK	Msil_1372	Msil_2955	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.649
Msil_1372	grpE	Msil_1372	Msil_2800	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.491
Msil_1372	htpG	Msil_1372	Msil_1910	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.491
Msil_1373	Msil_1372	Msil_1373	Msil_1372	PFAM: protein of unknown function DUF1150; KEGG: bid:Bind_0513 protein of unknown function DUF1150.	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	0.725
Msil_2366	Msil_1372	Msil_2366	Msil_1372	Type VI secretion ATPase, ClpV1 family; KEGG: bja:bll3587 ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	KEGG: mrd:Mrad2831_3162 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.	0.590
Msil_2366	dnaK	Msil_2366	Msil_2955	Type VI secretion ATPase, ClpV1 family; KEGG: bja:bll3587 ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.902
Msil_2366	grpE	Msil_2366	Msil_2800	Type VI secretion ATPase, ClpV1 family; KEGG: bja:bll3587 ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]	0.789
Msil_2366	htpG	Msil_2366	Msil_1910	Type VI secretion ATPase, ClpV1 family; KEGG: bja:bll3587 ATP-dependent Clp protease ATP-binding subunit; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.	Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.	0.705

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