STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msil_14794-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (346 aa)    
Predicted Functional Partners:
Msil_1478
Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.998
Msil_1477
4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ppf:Pput_2875 4-oxalocrotonate decarboxylase.
 
 
 0.995
Msil_3399
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bph:Bphy_1231 putative hydratase/decarboxylase.
 
 
 0.977
Msil_1480
4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: nar:Saro_3851 hydratase/decarboxylase.
 
  
 0.954
Msil_1481
PFAM: 4-oxalocrotonate tautomerase; KEGG: nar:Saro_3850 4-oxalocrotonate tautomerase.
 
   
 0.910
Msil_1474
TIGRFAM: catechol 2,3 dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: nar:Saro_3857 glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.861
Msil_0876
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rle:pRL120704 putative hydratase/decarboxylase.
 
  
 0.798
Msil_1473
PFAM: ferredoxin; KEGG: mpt:Mpe_A3312 hypothetical protein.
 
  
 0.790
Msil_1476
TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: dar:Daro_2775 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 0.772
Msil_1465
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: swi:Swit_3046 glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.747
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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