Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Msil_1646GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: bid:Bind_3392 GAF modulated sigma54 specific transcriptional regulator, fis family. (689 aa)    
Predicted Functional Partners:
Msil_0159
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.789
Msil_1645
Siderophore biosynthesis protein-like protein; KEGG: bid:Bind_3391 hypothetical protein.
       0.598
Msil_1650
PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: bid:Bind_3396 oxidoreductase FAD/NAD(P)-binding domain protein.
 
     0.509
Msil_1648
PFAM: monooxygenase component MmoB/DmpM; KEGG: bid:Bind_3394 phenol 2-monooxygenase.
 
     0.487
Msil_1647
Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.
       0.461
Msil_1649
PFAM: methane/phenol/toluene hydroxylase; KEGG: bid:Bind_3395 methane/phenol/toluene hydroxylase.
 
     0.444
Msil_1651
PFAM: methane/phenol/toluene hydroxylase; KEGG: bid:Bind_3397 methane monooxygenase.
 
   
 0.408
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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