Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_1950PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: cak:Caul_1999 UBA/ThiF-type NAD/FAD binding protein. (471 aa)    
Predicted Functional Partners:
Msil_1952
KEGG: cak:Caul_1997 hypothetical protein.
 
 
   0.972
Msil_1951
KEGG: cak:Caul_1998 hypothetical protein.
   
   0.890
Msil_1953
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: deh:cbdb_B6 hypothetical protein.
 
    0.816
Msil_1415
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: bid:Bind_2165 thiamine biosynthesis protein ThiS.
  
 
 0.812
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.805
Msil_1949
KEGG: mpo:Mpop_4132 hypothetical protein.
       0.786
Msil_1437
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: mlo:mlr7915 molybdopterin converting factor, subunit 2.
 
 0.773
Msil_1436
TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: rpb:RPB_1175 molybdopterin converting factor, subunit 1.
  
 
 0.764
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.656
Msil_3018
KEGG: bid:Bind_0125 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: protein of unknown function UPF0031; Phosphomethylpyrimidine kinase type-1.
  
  
 0.634
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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