STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msil_2131TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: gdi:GDI1919 adenosylmethionine--8-amino-7-oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (424 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 0.999
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.986
Msil_2132
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
 
 0.984
Msil_1353
8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: bid:Bind_3012 8-amino-7-oxononanoate synthase.
 
 
 0.958
Msil_2728
8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aminotransferase class I and II; aminotransferase class-III; KEGG: met:M446_0318 8-amino-7-oxononanoate synthase.
 
 
 0.957
Msil_1167
KEGG: bid:Bind_3210 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase class I and II.
 
  
 0.601
Msil_2030
5-aminolevulinic acid synthase; KEGG: pla:Plav_2905 5-aminolevulinate synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III.
 
  
 0.595
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
     
 0.551
Msil_1247
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_0846 amino acid adenylation domain protein.
  
  
0.514
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.496
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.