Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msil_2137PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cvi:CV_4394 ABC transporter ATP-binding protein. (312 aa)    
Predicted Functional Partners:
Msil_2139
PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: csa:Csal_2943 substrate-binding region of ABC-type glycine betaine transport system.
 
 0.999
Msil_2136
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sew:SeSA_A2400 inner membrane ABC transporter permease protein YehW.
 
 0.998
Msil_2138
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: csa:Csal_2944 binding-protein-dependent transport systems inner membrane component.
 
 0.998
Msil_2407
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cak:Caul_4410 ABC transporter related.
 
     
0.866
Msil_2140
KEGG: bid:Bind_3505 conserved hypothetical protein; putative deoxyribonuclease.
       0.776
Msil_2141
KEGG: scl:sce1235 hypothetical protein.
       0.525
Msil_2134
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: mex:Mext_3102 regulatory protein TetR.
       0.499
Msil_2135
PFAM: protein of unknown function DUF1348; KEGG: smt:Smal_2002 protein of unknown function DUF1348.
       0.499
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
     0.410
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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