STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msil_2175TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: aba:Acid345_1094 ParB-like partition proteins; Belongs to the ParB family. (322 aa)    
Predicted Functional Partners:
Msil_2590
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: met:M446_1408 cobyrinic acid ac-diamide synthase.
 
 
 0.919
Msil_2174
Hypothetical protein.
       0.773
Msil_2176
Adenine-specific DNA methylase-like protein; KEGG: bth:BT_2355 site-specific DNA-methyltransferase.
       0.773
rsmG
Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
 
  
 0.685
Msil_0327
PFAM: cell divisionFtsK/SpoIIIE; KEGG: bid:Bind_0464 cell divisionFtsK/SpoIIIE.
  
  
 0.585
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
   
 0.482
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.445
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.430
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
  
 0.423
Msil_3548
PFAM: Apolipoprotein A1/A4/E; KEGG: mrd:Mrad2831_1948 hypothetical protein.
  
 
 0.423
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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