Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Msil_2209TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: bid:Bind_0103 iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family. (119 aa)    
Predicted Functional Partners:
Msil_3621
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 0.938
Msil_0357
KEGG: bid:Bind_1575 nitrogen-fixing NifU domain protein.
  
 
 0.873
Msil_3549
PFAM: ferredoxin; KEGG: bid:Bind_2346 ferredoxin.
 
 0.825
Msil_1609
PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: bid:Bind_0097 aminotransferase class V.
 
 
 0.762
Msil_1100
TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: bid:Bind_0712 folate-binding protein YgfZ; Belongs to the GcvT family.
 
 
 0.743
Msil_3620
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
 
 
 0.728
purC-2
PFAM: SAICAR synthetase; KEGG: met:M446_3647 phosphoribosylaminoimidazolesuccinocarboxamide synthase.
 
      0.716
Msil_3644
PFAM: HesB/YadR/YfhF-family protein; KEGG: pna:Pnap_1576 iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
  
     0.680
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.630
Msil_1607
KEGG: bid:Bind_0099 FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase.
  
 
 0.626
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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