Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_2222PFAM: permease YjgP/YjgQ family protein; KEGG: bid:Bind_0651 permease YjgP/YjgQ family protein. (361 aa)    
Predicted Functional Partners:
Msil_0937
PFAM: permease YjgP/YjgQ family protein; KEGG: bid:Bind_0593 permease-like protein.
 
 0.995
Msil_0158
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bid:Bind_0568 ABC transporter related.
 
 
 0.985
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
 
  
 0.945
Msil_0072
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.691
Msil_3838
PFAM: transferase hexapeptide repeat containing protein; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; KEGG: met:M446_0641 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase.
 
     0.637
Msil_2220
PFAM: DNA polymerase III chi subunit HolC; KEGG: bid:Bind_0649 DNA polymerase III chi subunit HolC.
 
     0.621
Msil_2224
KEGG: bid:Bind_0653 hypothetical protein.
       0.606
Msil_2807
PFAM: protein of unknown function DUF140; KEGG: bid:Bind_3668 protein of unknown function DUF140.
   
 
 0.599
Msil_2892
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: bid:Bind_1061 transcriptional regulator, XRE family.
  
     0.576
Msil_0157
TIGRFAM: lipopolysaccharide transport periplasmic protein LptA; PFAM: OstA family protein; KEGG: bid:Bind_0570 OstA family protein.
 
   
 0.545
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
Server load: low (18%) [HD]