Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lptDOrganic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (889 aa)    
Predicted Functional Partners:
Msil_2222
PFAM: permease YjgP/YjgQ family protein; KEGG: bid:Bind_0651 permease YjgP/YjgQ family protein.
 
  
 0.945
Msil_0157
TIGRFAM: lipopolysaccharide transport periplasmic protein LptA; PFAM: OstA family protein; KEGG: bid:Bind_0570 OstA family protein.
 
 
 0.927
Msil_2224
KEGG: bid:Bind_0653 hypothetical protein.
 
  
 0.836
bamA
Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.823
Msil_0329
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
   
 0.787
Msil_0937
PFAM: permease YjgP/YjgQ family protein; KEGG: bid:Bind_0593 permease-like protein.
 
  
 0.777
Msil_0156
PFAM: protein of unknown function DUF1239; KEGG: bid:Bind_0571 protein of unknown function DUF1239.
 
   
 0.764
Msil_0132
KEGG: bid:Bind_3675 hypothetical protein.
  
     0.761
Msil_0507
PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: bid:Bind_1449 PpiC-type peptidyl-prolyl cis-trans isomerase.
 
  
 0.760
Msil_0121
KEGG: bid:Bind_0880 hypothetical protein.
  
    0.746
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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