Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_2248PFAM: glycoside hydrolase family 3 domain protein; KEGG: bid:Bind_0865 glycoside hydrolase family 3 domain protein. (365 aa)    
Predicted Functional Partners:
anmK
Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
   
 0.643
Msil_3815
KEGG: bid:Bind_0051 hypothetical protein.
  
  
 0.577
Msil_2247
Transcriptional regulator, ModE family; PFAM: regulatory protein LysR; TOBE domain protein; KEGG: bid:Bind_2034 transcriptional regulator, ModE family.
       0.574
Msil_1420
PFAM: major facilitator superfamily MFS_1; KEGG: mrd:Mrad2831_1648 major facilitator superfamily MFS_1.
 
   
 0.514
Msil_3875
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bid:Bind_3031 glutamate synthase (ferredoxin).
 
   
 0.472
Msil_2249
KEGG: bxe:Bxe_B2600 hypothetical protein.
       0.469
Msil_2246
TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: bid:Bind_1572 sulfate ABC transporter, periplasmic sulfate-binding protein.
       0.420
Msil_1341
Peptidase M23; PFAM: Peptidoglycan-binding LysM; Peptidase M23; KEGG: bid:Bind_2699 peptidase M23.
 
  
 0.413
Msil_3546
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mrd:Mrad2831_2007 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD.
     
 0.403
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
     
 0.402
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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