Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_2268PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rle:pRL120615 putative hydroxypyruvate isomerase; Belongs to the hyi family. (281 aa)    
Predicted Functional Partners:
Msil_2267
PFAM: Rubrerythrin; protein of unknown function DUF125 transmembrane; KEGG: bid:Bind_3443 rubrerythrin.
 
     0.579
Msil_2269
PFAM: GCN5-related N-acetyltransferase; KEGG: bid:Bind_3422 GCN5-related N-acetyltransferase.
       0.572
Msil_1068
PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rpc:RPC_2065 3-hydroxyisobutyrate dehydrogenase.
  
 0.571
Msil_1715
Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: mpt:Mpe_A3263 glycerate 2-kinase.
 
  
 0.492
Msil_2266
PFAM: metallophosphoesterase; KEGG: bid:Bind_3442 metallophosphoesterase.
       0.481
Msil_1122
PFAM: class II aldolase/adducin family protein; KEGG: mex:Mext_4772 L-fuculose-phosphate aldolase.
 
  
 0.448
Msil_2598
PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mva:Mvan_5187 6-phosphogluconate dehydrogenase, NAD-binding.
 
  
 0.447
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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