Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Msil_2332PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: mms:mma_0955 glutathione-regulated potassium-efflux system protein KefB; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (568 aa)    
Predicted Functional Partners:
Msil_2331
PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: aba:Acid345_1748 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.826
Msil_0402
PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: pol:Bpro_2149 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
0.734
Msil_2987
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: pzu:PHZ_p0134 pyruvate:ferredoxin oxidoreductase.
  
 
 0.723
Msil_0027
TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: bid:Bind_3653 flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.
    
   0.702
Msil_1655
PFAM: protein of unknown function DUF1217; KEGG: bid:Bind_2809 protein of unknown function DUF1217.
    
   0.702
Msil_1656
PFAM: flagellar basal body rod protein; KEGG: bid:Bind_2810 flagellar basal body rod protein.
    
   0.702
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.700
Msil_2984
Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
   
 
 0.685
Msil_1315
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: pol:Bpro_1191 ATPase, E1-E2 type.
 
 
 0.683
Msil_1572
Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: bid:Bind_2679 heavy metal translocating P-type ATPase.
  
  
 0.681
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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