Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Msil_2382PFAM: TPR repeat-containing protein; peptidase C14 caspase catalytic subunit p20; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: met:M446_6666 peptidase C14 caspase catalytic subunit P20. (778 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.919
Msil_0644
PFAM: Peptidase M23; KEGG: bid:Bind_2932 peptidase M23.
   
   0.796
Msil_1418
PFAM: transcriptional regulator domain protein; KEGG: met:M446_5608 transcriptional regulator, CadC.
   
 
 0.789
Msil_2322
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bid:Bind_3201 TPR repeat-containing protein.
 
 
 
0.778
Msil_1891
KEGG: bbt:BBta_7846 hypothetical protein.
     0.726
Msil_1117
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bid:Bind_0857 tetratricopeptide TPR_2 repeat protein.
 
 
 
 0.719
Msil_2380
PFAM: GumN family protein; KEGG: met:M446_6668 GumN family protein.
 
     0.691
Msil_2124
Serine/threonine protein kinase; PFAM: protein of unknown function RIO1; tyrosine protein kinase; protein of unknown function DUF323; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: met:M446_0913 serine/threonine protein kinase.
    0.656
Msil_2473
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_5171 GAF sensor hybrid histidine kinase.
     
 0.640
Msil_2726
PFAM: glycosyl transferase family 2; KEGG: bid:Bind_0447 glycosyl transferase family 2.
 
   
 0.639
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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