Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_2406PFAM: transcriptional coactivator/pterin dehydratase; KEGG: bph:Bphy_6480 transcriptional coactivator/pterin dehydratase. (127 aa)    
Predicted Functional Partners:
Msil_2396
PFAM: dihydroneopterin aldolase; protein of unknown function DUF556; KEGG: gbe:GbCGDNIH1_0762 dihydroneopterin aldolase.
 
   
 0.840
Msil_2400
KEGG: gbe:GbCGDNIH1_0778 tungsten-containing formylmethanofuran dehydrogenase, subunit B.
 
   
 0.795
Msil_2389
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: met:M446_5782 triphosphoribosyl-dephospho-CoA protein.
 
     0.789
Msil_2384
TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: mca:MCA2861 GHMP family kinase.
 
     0.786
Msil_2385
Methylenetetrahydrofolate dehydrogenase (NADP(+)); PFAM: Methylene-tetrahydromethanopterin dehydrogenase; KEGG: gbe:GbCGDNIH1_0775 methylenetetrahydromethanopterin dehydrogenase (NAD+/NADP+).
 
     0.776
Msil_2393
PFAM: protein of unknown function DUF447; KEGG: gbe:GbCGDNIH1_0766 hypothetical protein.
 
   
 0.773
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
     0.748
Msil_2386
PFAM: protein of unknown function DUF201; KEGG: mrd:Mrad2831_0529 protein of unknown function DUF201.
 
     0.739
Msil_2394
PFAM: dihydropteroate synthase DHPS; KEGG: met:M446_5017 dihydropteroate synthase DhpS.
 
    0.735
Msil_2403
TIGRFAM: formylmethanofuran dehydrogenase subunit C; PFAM: glutamate synthase alpha subunit domain protein; KEGG: gbe:GbCGDNIH1_0781 tungsten-containing formylmethanofuran dehydrogenase, subunit C.
 
     0.731
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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