Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Msil_2467PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: mpo:Mpop_0793 tetratricopeptide TPR_2 repeat protein. (273 aa)    
Predicted Functional Partners:
Msil_2466
KEGG: met:M446_1389 hypothetical protein.
 
 
 0.951
Msil_2471
PFAM: protein of unknown function DUF58; KEGG: met:M446_1384 hypothetical protein.
 
    0.949
Msil_2468
KEGG: met:M446_1387 von Willebrand factor type A.
 
     0.946
Msil_2469
PFAM: von Willebrand factor type A; KEGG: mrd:Mrad2831_4305 von Willebrand factor type A.
 
   
 0.946
Msil_2472
PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: met:M446_1383 ATPase associated with various cellular activities AAA_3.
 
     0.875
Msil_3219
KEGG: smd:Smed_3799 protein of unknown function DUF58.
 
    0.781
Msil_2470
KEGG: mex:Mext_0864 hypothetical protein.
       0.778
Msil_2473
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_5171 GAF sensor hybrid histidine kinase.
   
 
 0.521
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
   
 0.496
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
 
 
 0.471
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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