Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_2495PFAM: Rieske [2Fe-2S] domain protein; KEGG: xau:Xaut_0130 Rieske (2Fe-2S) domain-containing protein. (151 aa)    
Predicted Functional Partners:
Msil_3024
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.619
Msil_1509
TIGRFAM: nitrate reductase, beta subunit; KEGG: mrd:Mrad2831_2591 nitrate reductase, beta subunit.
  
  
 0.491
Msil_2496
KEGG: xau:Xaut_0128 hypothetical protein.
       0.471
Msil_3621
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.459
Msil_0457
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bcm:Bcenmc03_6887 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.415
Msil_1470
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: smd:Smed_5005 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.415
Msil_3220
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rieske [2Fe-2S] domain protein; KEGG: bid:Bind_0566 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.415
Msil_3774
TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: scl:sce3488 nitrite reductase.
  
  
 0.415
Msil_1508
TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: azc:AZC_1427 nitrate reductase delta subunit protein.
  
  
 0.406
Msil_3875
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bid:Bind_3031 glutamate synthase (ferredoxin).
   
  
 0.400
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.