Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_2541PFAM: FAD linked oxidase domain protein; KEGG: mlo:mlr6919 glycolate oxidase subunits GlcE. (401 aa)    
Predicted Functional Partners:
Msil_2540
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: oan:Oant_3012 protein of unknown function DUF224 cysteine-rich region domain protein.
 
 
 0.995
Msil_1695
PFAM: FAD linked oxidase domain protein; KEGG: oan:Oant_3010 D-lactate dehydrogenase (cytochrome).
  
 
0.939
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
 
 0.930
Msil_1714
PFAM: aminotransferase class V; KEGG: met:M446_6552 serine--glyoxylate transaminase.
 
 
  0.916
Msil_3400
Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: bid:Bind_3524 serine--glyoxylate transaminase.
 
 
  0.915
Msil_1123
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: rme:Rmet_4768 2-keto-3-deoxy-phosphogluconate aldolase.
   
 
 0.908
Msil_1713
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: met:M446_6553 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
   
 0.907
Msil_2485
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: bid:Bind_0511 glyoxylate reductase.
   
 0.907
gph
HAD-superfamily hydrolase, subfamily IA, variant 1; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
 0.904
Msil_2100
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: bid:Bind_1313 HAD-superfamily hydrolase, subfamily IA, variant 1.
    
 0.904
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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