Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_2622PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase putative; KEGG: bja:blr4116 hypothetical protein. (603 aa)    
Predicted Functional Partners:
Msil_2621
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: bja:blr4117 DNA polymerase III subunit epsilon.
 
    0.982
Msil_2623
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: bja:blr4115 acetate permease; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.961
Msil_2624
PFAM: protein of unknown function DUF485; KEGG: bja:blr4114 hypothetical protein.
 
  
 0.954
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.490
Msil_2699
KEGG: bac:BamMC406_3901 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
   
 0.486
Msil_3875
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bid:Bind_3031 glutamate synthase (ferredoxin).
     
 0.434
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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