Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_2884PFAM: peptidase C14 caspase catalytic subunit p20; KEGG: met:M446_0920 peptidase C14 caspase catalytic subunit P20. (1155 aa)    
Predicted Functional Partners:
Msil_2883
TIGRFAM: type VI secretion system FHA domain protein; PFAM: Forkhead-associated protein; KEGG: bja:blr3598 hypothetical protein.
 
     0.625
Msil_2882
TIGRFAM: type IV / VI secretion system protein, DotU family; type VI secretion system OmpA/MotB family protein; PFAM: OmpA/MotB domain protein; KEGG: bja:blr3600 hypothetical protein.
 
     0.493
Msil_2880
TIGRFAM: type VI secretion-associated protein, BMA_A0400 family; KEGG: bja:blr3602 hypothetical protein.
 
     0.483
Msil_2124
Serine/threonine protein kinase; PFAM: protein of unknown function RIO1; tyrosine protein kinase; protein of unknown function DUF323; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: met:M446_0913 serine/threonine protein kinase.
 
     0.475
Msil_2881
TIGRFAM: type VI secretion protein IcmF; PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: bja:blr3601 hypothetical protein.
 
     0.446
Msil_2879
PFAM: Stage II sporulation E family protein; Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: met:M446_0912 protein serine/threonine phosphatase.
 
     0.444
Msil_2878
PFAM: tyrosine protein kinase; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: bja:blr3604 serine/threonine kinase.
 
     0.431
Msil_3163
Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: sme:SMc02176 putative adenylate cyclase transmembrane protein.
 
     0.411
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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