Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_2899PFAM: peptidase M22 glycoprotease; KEGG: bid:Bind_1052 peptidase M22 glycoprotease. (234 aa)    
Predicted Functional Partners:
Msil_0666
PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: bid:Bind_0587 protein of unknown function UPF0079.
 
 
 0.986
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.946
Msil_2898
PFAM: GCN5-related N-acetyltransferase; KEGG: bid:Bind_1053 GCN5-related N-acetyltransferase.
  
 
 0.873
Msil_2900
Scaffold protein Nfu/NifU; PFAM: nitrogen-fixing NifU domain protein; Scaffold protein Nfu/NifU; KEGG: bid:Bind_1051 scaffold protein Nfu/NifU.
       0.727
Msil_0445
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
    
 0.720
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
     
 0.670
Msil_2896
PFAM: PhoH family protein; KEGG: bid:Bind_1056 PhoH family protein.
 
     0.668
miaB
RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
  
 0.668
Msil_2894
PFAM: CBS domain containing protein; transporter-associated region; KEGG: bid:Bind_1058 CBS domain containing protein.
  
    0.640
Msil_2932
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: bid:Bind_2384 biotin--acetyl-CoA-carboxylase ligase.
  
    0.628
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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