Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Msil_3140Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: nwi:Nwi_0662 XRE family transcriptional regulator. (206 aa)    
Predicted Functional Partners:
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
  
  
 0.555
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.491
Msil_1247
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_0846 amino acid adenylation domain protein.
     
 0.487
Msil_3875
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bid:Bind_3031 glutamate synthase (ferredoxin).
     
 0.487
Msil_2636
TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: azc:AZC_1496 sarcosine oxidase beta subunit.
 
  
 0.482
Msil_3139
TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: mag:amb1054 transcriptional regulator.
  
  
 0.451
Msil_2638
TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mpo:Mpop_1579 sarcosine oxidase, alpha subunit family; Belongs to the GcvT family.
 
   
 0.448
Msil_0552
PFAM: Silent information regulator protein Sir2; KEGG: bid:Bind_1553 silent information regulator protein Sir2.
  
    0.447
Msil_1395
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: pst:PSPTO_3517 multifunctional fatty acid oxidation complex subunit alpha.
  
  
 0.431
Msil_1742
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: bid:Bind_1755 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
  
 0.431
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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