Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_3200PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: gbe:GbCGDNIH1_1055 dioxygenase. (270 aa)    
Predicted Functional Partners:
Msil_3201
PFAM: YceI family protein; KEGG: mrd:Mrad2831_5251 YceI family protein; Belongs to the UPF0312 family.
     
 0.791
Msil_3202
PFAM: cytochrome B561; KEGG: gdi:GDI1482 putative cytochrome b561.
  
  
 0.787
Msil_3203
PFAM: YceI family protein; KEGG: mrd:Mrad2831_5253 YceI family protein; Belongs to the UPF0312 family.
     
 0.760
Msil_3215
PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: rpb:RPB_4505 pirin-like protein; Belongs to the pirin family.
 
  
 0.676
Msil_2562
PFAM: Pirin domain protein; KEGG: nwi:Nwi_0616 pirin; Belongs to the pirin family.
 
  
 0.641
Msil_0430
PFAM: Rhodanese domain protein; KEGG: bid:Bind_1219 rhodanese domain protein.
 
    
 0.631
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.565
Msil_3199
PFAM: OsmC family protein; KEGG: ppg:PputGB1_0104 OsmC family protein.
  
    0.549
Msil_3204
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rpc:RPC_2324 transcriptional regulator, LysR family.
       0.519
Msil_2108
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.400
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
Server load: low (10%) [HD]