Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_3205PFAM: tyrosine protein kinase; Protein phosphatase 2C-like; Serine/threonine protein kinase-related; SMART: protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: mca:MCA0593 protein phosphatase/kinase family protein. (571 aa)    
Predicted Functional Partners:
Msil_0520
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.947
Msil_2356
KEGG: bja:blr3597 hypothetical protein.
  
 
 0.848
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
  
 
 0.796
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
   0.781
Msil_1771
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: azc:AZC_3408 ATPase.
 
 
 0.749
Msil_0500
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: mex:Mext_0324 MIP family channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.739
Msil_1074
PFAM: peptidase C15 pyroglutamyl peptidase I; KEGG: bid:Bind_1658 peptidase C15 pyroglutamyl peptidase I.
    
   0.729
Msil_2124
Serine/threonine protein kinase; PFAM: protein of unknown function RIO1; tyrosine protein kinase; protein of unknown function DUF323; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: met:M446_0913 serine/threonine protein kinase.
 
 
0.725
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 
 0.717
Msil_1972
KEGG: nha:Nham_0594 hypothetical protein.
  
 0.717
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.