STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Msil_3205PFAM: tyrosine protein kinase; Protein phosphatase 2C-like; Serine/threonine protein kinase-related; SMART: protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: mca:MCA0593 protein phosphatase/kinase family protein. (571 aa)    
Predicted Functional Partners:
Msil_0520
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.980
Msil_2356
KEGG: bja:blr3597 hypothetical protein.
  
 
 0.829
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
   0.800
Msil_2124
Serine/threonine protein kinase; PFAM: protein of unknown function RIO1; tyrosine protein kinase; protein of unknown function DUF323; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: met:M446_0913 serine/threonine protein kinase.
 
 
0.769
Msil_0500
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: mex:Mext_0324 MIP family channel protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.660
Msil_1326
PFAM: Fmu (Sun) domain protein; KEGG: bid:Bind_1921 Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.657
Msil_1424
TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: bid:Bind_2071 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.657
Msil_2001
Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bja:bll0966 two-component hybrid sensor and regulator.
 
 
 0.648
Msil_3771
PFAM: major facilitator superfamily MFS_1; KEGG: azo:azo1288 putative nitrate transporter.
 
    0.643
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
  
 
 0.626
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.