Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_3443Transcriptional regulator, CdaR; PFAM: GAF domain protein; KEGG: mpt:Mpe_B0495 transcriptional regulator, CdaR family. (741 aa)    
Predicted Functional Partners:
Msil_3441
KEGG: mpt:Mpe_B0535 hypothetical protein.
 
     0.620
Msil_2473
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_5171 GAF sensor hybrid histidine kinase.
   
 
 0.617
Msil_2474
Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rle:pRL120719 two-component histidine kinase/response regulator motif-containing protein.
     
 0.591
Msil_3440
KEGG: mpt:Mpe_B0532 hypothetical protein.
       0.542
Msil_3442
PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: mpt:Mpe_B0506 pyruvate phosphate dikinase.
       0.542
Msil_2699
KEGG: bac:BamMC406_3901 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.481
Msil_3437
KEGG: mpt:Mpe_B0503 hypothetical protein.
 
     0.461
Msil_2700
Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: rpc:RPC_1464 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains).
 
  
 0.459
Msil_3402
D-lactate dehydrogenase (cytochrome); PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; FAD linked oxidase domain protein; KEGG: bja:blr6041 putative glycolate oxidase.
     
 0.451
Msil_3439
KEGG: mpt:Mpe_B0534 hypothetical protein.
       0.449
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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