Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_3535ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (174 aa)    
Predicted Functional Partners:
Msil_3556
PFAM: Glutathione S-transferase domain; KEGG: bur:Bcep18194_C7686 glutathione S-transferase-like protein; Belongs to the GST superfamily.
  
  
  0.925
Msil_2818
PFAM: Glutathione S-transferase domain; KEGG: smd:Smed_5294 glutathione S-transferase domain.
  
  
  0.917
Msil_3681
PFAM: Glutathione S-transferase domain; KEGG: bid:Bind_3313 glutathione S-transferase domain.
  
  
  0.917
Msil_0624
PFAM: Glutathione S-transferase domain; KEGG: bid:Bind_1959 glutathione S-transferase domain.
  
  
  0.916
Msil_0122
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
  
  
 0.912
Msil_2383
PFAM: Glutathione S-transferase domain; KEGG: pol:Bpro_3007 glutathione S-transferase-like.
  
  
  0.912
Msil_1590
PFAM: Glutathione S-transferase domain; KEGG: azc:AZC_3140 putative glutathione S-transferase family protein.
  
  
  0.911
gshB
KEGG: bid:Bind_3126 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
     
 0.907
Msil_0016
KEGG: bid:Bind_3633 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
   
 
 0.900
Msil_0194
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: bid:Bind_0850 aminopeptidase N.
     
 0.900
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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